While in several studies, it has been reported that during development of pancreatic cancer the expression of SDF-1 increases within pancreatic tissue 24, 25, results of our study demonstrate that SDF-1 does not seem to be associated with intensified peripheral trafficking of BMSCs in patients with pancreatic cancer and its systemic concentrations are comparable to those observed in healthy individuals. Here, CXCL12 is linked to pancreatic neoplasm.