All patients with diabetes were divided according to the activity of vWF into EDvWF− (vWF < 110%) and EDvWF+ (vWF > 110%) subgroups, according to the concentration of ICAM-1 into EDICAM-1− (ICAM-1 < 300 μg/L) and EDICAM-1+ (ICAM-1 > 300 μg/L), and according to the concentration of VCAM-1 into EDVCAM-1− (VCAM-1 < 800 μg/L) and EDVCAM-1+ (VCAM-1 > 800 μg/L), respectively. The gene discussed is VWF; the disease is diabetes mellitus.