VWF and endothelial dysfunction: The aim of this study was to compare AGEs levels in the skin measured by AGE-Reader with biochemical markers of endothelial dysfunction (vWF, ICAM, VCAM, E-selectin, and P-selectin) and sRAGE levels in Type 1 and Type 2 patients with diabetes, to search for a relationship between AGE/RAGE axis and endothelial function.