IGF1 and diabetes mellitus: There was no significant difference in IGF-1 changes from initial to final values in terms of patient age, duration of diabetes mellitus, Wagner grade, initial HbA1C value, final HbA1C value, or HbA1C alterations (P  values were 0.93, 0.46, 0.76, 0.88, 0.70, and 0.40, resp).