When patients with PDR were divided into those with or without hemorrhage, the mean levels of angiogenic and vasculogenic factors differed significantly between PDR patients with hemorrhage, PDR patients without hemorrhage, and nondiabetic control patients for VEGF (P < 0.001), sVEGFR-2 (P = 0.003), SCF (P = 0.001), s-kit (P = 0.001), and PGE2 (P < 0.001) (Table 3). Here, KITLG is linked to hemorrhage.