However, chronic oversecretion of stress mediators, for example glucocorticoids (GCs) such as cortisol, as well as catecholamines, may result in problems such as hyperinsulinaemia and growth hormone and sex steroid hyposecretion, leading to visceral adiposity, loss of muscle (sarcopenia), arterial hypertension, glucose intolerance, and dyslipidemia, and therefore, MetS [7–10]. The gene discussed is GH1; the disease is metabolic syndrome.