In conclusion, the present study suggested that FA enhances the sensitization of Balb/c mice to inhaled allergens and that it might be an underlying risk factor for an increase in asthma severity; Further, TRPV1, TRPA1 and neuropeptides play a key part in the adjuvant effect of FA-promoted asthma or asthma-like symptoms. Here, TRPA1 is linked to asthma.