PLG and endometriosis: Other authors [29] state the importance of neoangiogenesis in the development of endometriosis, and the possible role of anti-angiogenic therapy: they use a murine model of endometriosis and administered an adenovirus vector to overexpress the gene for a natural angiogenesis inhibitor angiostatin, and found that the disease was eradicated in all endometriosis-induced mouse.