As shown in Supplementary Table S3, see section on supplementary data given at the end of this article, the classification based on H19 and TARBP2 expression had similar levels of sensitivity (SEN=93% for both H19 and TARBP2) and specificity (SPE=79% for both H19 and TARBP2), while IGF2 showed a slightly lower sensitivity (89%) and specificity (77%) when compared with TARBP2. The combination of TARBP2, IGF2, and H19 expressions had an additive effect in the predictive value for ACC (SEN=97% and SPE=81%). This evidence concerns the gene IGF2 and adrenal cortex carcinoma.