Significant over-expression of TARBP2 (1.3- to 4-fold, P<0.0001), DICER (0.4- to 5-fold, P<0.0001), and DROSHA (0.2- to 4.5-fold, P<0.0001) was also observed in carcinomas when compared with adenomas (Fig. 1A). Here, DROSHA is linked to carcinoma.