It is also noteworthy that the levels of NCoR and NCoR phosphorylation is elevated in LNCaP-derivative C4-2B cells compared with LNCaP cells, although to a less than both DU145 and PC-3 cells, implying the plausible role of CK2-NCoR cascade in hormone independency of prostate cancer cells (Supplementary Figure 1). The gene discussed is NCOR1; the disease is prostate cancer.