APOB and familial hyperaldosteronism: The clinical phenotype of FH is known to be due to mutations in three genes encoding proteins involved in the uptake of LDL-C from the plasma, LDLR, APOB and PCSK9. In the UK, the Simon Broome Register criteria are used for the clinical diagnosis of FH, whereas other European countries may use a score developed by the Dutch Lipid Clinic Network (DLCN) [1,3].