Allogeneic or autologous lymphocytes (autolymphocytes) used by ACI range from tightly defined specificity, e.g., tumor antigen-specific cytotoxic T lymphocytes (CTL) and genetically engineered T cells to broad phenotype and activity, e.g., lymphokine-activated killer (LAK) cells, tumor-infiltrating lymphocytes (TIL) and cytokine-induced killer (CIK) cells, which are heterogeneous effector cell population characterized by co-expression of CD3 and CD56 molecules [5]–[8]. The gene discussed is NCAM1; the disease is neoplasm.