BCL-2 family proteins act as regulators of cell survival in a variety of cancers, including non-small cell lung cancer and breast cancer [17], [18], colon adenocarcinomas [19], clear-cell renal cell carcinoma [20], non-Hodgkin B-cell lymphoma [21], and other hematopoietic malignancies [22]. The gene discussed is BCL2; the disease is breast carcinoma.