RBX1 and urinary bladder carcinoma: Our data showed that ROC1 protein was weakly expressed in 18 of 24 (75%) normal bladder urothelium, whereas ROC1 protein was highly expressed in bladder cancer tissues (Fig. 1), i.e., among these 112 BTCC tissue specimens, ROC1 protein was moderately or strongly expressed in 29 (25.9%), and 66 (58.9%) samples, respectively.