ANGPTL2 and metabolic syndrome: A recent study, however, demonstrated that levels of angptl2 reflect adiposity and might regulate inflammation and triglyceride metabolism.34 Although inflammation triggers atherosclerosis in animal models of dyslipidemia,32 it is not possible at this stage to decipher whether the premature atherogenic response induced by angptl2 is a result of its proinflammatory or its hypercholesterolemic effect.