A significant negative correlation was found between NM modulation of Matrigel invasion inhibition and MMP-2 secretion with fibrosarcoma HT-1080 (r=−0.911), chondrosarcoma SW-1353 (r=−0.942), liposarcoma SW-872 (r=−0.957) and synovial sarcoma SW-982 (r=−0.878). Here, MMP2 is linked to chondrosarcoma.