BSCL2 and congenital generalized lipodystrophy type 2: Pathogenic variants of homologous to mouse gamma-3-linked (BSCL2, MIM 606158) gene, located at chromosome 11q13, cause congenital generalized lipodystrophy type 2 (CGL2, MIM 269700) or a seipin-deficient phenotype [3,5].