The level of galectin-3 expression in relation to neoplastic progression of hypopharyngeal squamous cell carcinomas (HSCCs) and laryngeal squamous cell carcinomas (LSCCs) demonstrate an association between the level of galectin-3 expression and neoplastic progression in these carcinomas [72]. The gene discussed is LGALS3; the disease is hypopharynx squamous cell carcinoma.