ALB and liver dysplastic nodule: It is in concert with our previous results that all diabetic rats in this experiment presented the early stage of DN, such as the increase of relative kidney weight, tubulointerstitial fibrosis, urinary albumin and urinary glucose after 30 days induction of STZ[13], while BCM7 treatment provided renoprotection with decreased urinary albumin and urinary glucose, alleviated tubulointerstitial fibrosis without changing blood glucose levels[13].