ACP3 and metastatic prostate carcinoma: Sipuleucel-T, an active immunotherapy comprised of autologous dendritic cells (DC) pulsed with a fusion protein composed of granulocyte macrophage colony-stimulating factor (GM-CSF) and prostatic acid phosphatase (PAP), was shown to provide a significant increase in overall survival in patients with metastatic prostate cancer (Kantoff et al., 2010).