Sipuleucel-T, an active immunotherapy comprised of autologous dendritic cells (DC) pulsed with a fusion protein composed of granulocyte macrophage colony-stimulating factor (GM-CSF) and prostatic acid phosphatase (PAP), was shown to provide a significant increase in overall survival in patients with metastatic prostate cancer (Kantoff et al., 2010). This evidence concerns the gene CSF2 and metastatic prostate carcinoma.