GPT and diabetes mellitus: In another study, metabolic changes (lipid, liver enzymes, blood pressure, and body weight) potentially associated with conversion to diabetes were investigated, it was found that in subjects who converted to new-onset diabetes, ALT (P = 0.0005) and triglycerides' (P = 0.030) concentrations are increased in absence of changes in body weight up to 18 months before the diabetes manifestation, but neither parameters increased significantly in nonconverters with high baseline glucose concentrations (>6.1 mmol/L) [17].