From this list, DPP4, IL2RA, RAB31, PTPRD, CACNA1D, IL1RAP, SLC4A4, and KCNK5 were upregulated in the CML CD34+CD38−ALDHhigh population and exhibit a cell surface protein localization. This evidence concerns the gene KCNK5 and chronic myelogenous leukemia, BCR-ABL1 positive.