This study demonstrated dendritic cells infected with mammaglobin-A recombinant adenovirus specifically elicited mammaglobin-A specifically stimulated CD8+ cytotoxic T lymphocytes against HLA-A33+/MGBA+ breast cancer cells in vitro, suggesting that it may be further developed as a novel strategy for immunotherapy of MGBA-positive breast cancers. The gene discussed is CD8A; the disease is breast carcinoma.