As expected, FGFR3 immunohistochemical scores were significantly associated with FGFR3 mutations (ANOVA P = 3×10−5, KW P = 3×10−4) and were higher in the low grade NMIBC than in the more aggressive tumor groups of high grade NMIBC and MIBC (ANOVA P = 0.038, KW P = 0.026). Here, FGFR3 is linked to neoplasm.