The Odontogenic Ameloblast-Associated Protein (ODAM) was first identified less than a decade ago as the protein constituent of calcifying epithelial odontogenic/Pindborg tumors (CEOT) and subsequent studies revealed that it is highly expressed in mature ameloblasts and present in the rodent enamel organ and junctional epithelium [10-13]. Here, ODAM is linked to calcifying epithelial odontogenic tumor.