As Ets1 had not been confirmed as a target of miR-1 in the mouse, and since several studies support a role of Ets1 in cSCC and cancer phenotypes such as metastasis, apoptosis and proliferation, we decided to further evaluate murine Ets1 as a miR-1 target (Keehn, Smoller & Morgan, 2004; Hahne et al., 2009; Nagarajan et al., 2009). The gene discussed is ETS1; the disease is cancer.