Treatment with losartan or captopril was started immediately after infection, in a dose at least 10 or 20 times above the IC50 for Captopril (IC50 = 1.940 mg/Kg/d) or Losartan (IC50 = 0.966 mg/Kg/d), respectively in relation to CD69 expression (Fig. S1). This evidence concerns the gene CD69 and infection.