However, the inhibition of various proinflammatory mediators such as IL-4, IL-13, TGF-β1, 15-LOX, and reduction of 15-LOX metabolites such as 13-(S)-HODE and 9-(S)-HODE, are likely to lead to reduction of bronchial epithelial injury and consequent airway remodeling could be possible mechanisms by which baicalein reduces asthma features. This evidence concerns the gene TGFB1 and asthma.