PF4 and diabetes mellitus: Although the diabetic MHD patients in this study were significantly more likely than the non-diabetic patients to undergo more than three dialyses per week (97/127 cases, 76.4% vs 355/530 cases, 67.0%, respectively; P = 0.043), the positivity rate of the anti-PF4/heparin antibody was significantly increased in the diabetic patients with MHD, which differs from the conclusion of Diaz J et al.[29] that diabetes does not increase the positivity rate of the anti-PF4/heparin antibody.