FH and renal carcinoma: We then analyzed two panels of isogenic FH-deficient lines; FH1KOMEFs reconstituted with either FH or FHcyt (O’Flaherty et al., 2010) and UOK262 (derived from a metastasis from an FH mutant renal cancer (Yang et al., 2010b), which we have genetically complemented with the same FH or FHcyt constructs (Figure S2).