CRP and neoplasm: However, focusing on the subgroup of patients without metastasis, both advanced local tumor stage (≥pT2; HR 8.78, 95% CI 1.1-70.7, p=0.041) and an elevated CRP value (>15 mg/l; HR 3.34, 95% CI 1.04-10.7, p=0.043) were identified as predictors of poor clinical outcome in patients with penile cancer (Table 2).