To explore relationships between bile acids and non-invasive markers of liver fibrosis in HIV patients on ART, we calculated FIB-4 (age [years] × AST [IU/L]/platelet count [109/L] × (ALT1/2[IU/L])) and AST-Platelets Ratio Index (APRI) (AST [IU/L]/platelet count [109/L]) scores, evaluated YKL-40 levels in plasma, and examined associations between these markers and alterations in bile acids. This evidence concerns the gene CHI3L1 and Hepatic fibrosis.