An immunocytochemical study conducted in the Amazon region found that CD8+ T cells occurred at a higher level in all forms of the disease except mucocutaneous leishmaniasis, and included cases of cutaneous lesions caused by L. braziliensis. Its results seem to corroborate the role of CD8+ T cells in a balanced immune response to cutaneous lesions and, probably, in the healing process [23]. Here, CD8A is linked to mucocutaneous leishmaniasis.