HLA-A*01 was more frequent in patients from subgroup 3B (28.6% vs. 9% [P = 0.0360; Pc = 0.6480; OR = 4.0255; 95%CI = 1.2153 – 13.3341]), as was HLA-B*52 (21.4% vs. 2.1% [P = 0.0044; Pc = 0.1364; OR = 12.6198; 95%CI = 3.0827 – 51.6619]), suggesting possible susceptibility to relapse of cutaneous ACL at a location remote from the site of previous infection. This evidence concerns the gene HLA-A and infection.