In these donors, no differences in IL6 and TNFα production were observed upon EV1 infection (data not shown), confirming previous reports that induction of cytokines and upregulation of costimulatory molecules are separate processes [31], [32], since CD80 and PDL1 were differentially induced upon EV1 infection in BDCA1+ mDCs versus moDCs. This evidence concerns the gene CD1C and infection.