Our meta-analysis of published Brazilian infection-without-disease tuberculosis surveys, including tuberculin skin tests (TST) [69]–[72] and, in one case, TST plus an IFN-γ release assay [73], revealed a marginally non-significant male bias in exposure to Mycobacterium tuberculosis (random-effects OR 1.16, 95%CI 1.00–1.36; N = 6725 subjects; Figure 4). This evidence concerns the gene IFNG and tuberculosis.