The Th2 cytokines IL-4 and IL-13, which play a critical role in asthma, “alternatively” activate macrophages and induce receptors, cytokines, enzymes, and change phagocytosis, proliferation, and other cellular processes that enable AAMs to regulate their surrounding leukocytes, parenchymal cells, and environment [3]–[5]. This evidence concerns the gene IL4 and asthma.