Nine of the 72 SNPs in the BCL2 gene (rs12961976, rs17759659, rs2170294, rs4941195, rs4987768, rs7230177, rs7231901, rs7243091 and rs9807663) had a statistically significant association with endometrial cancer risk (P<0.05, Table 3), all of which are intronic to BCL2. These 9 SNPs lie in 4 haplotype blocks in the BCL2 genomic region and r2 values were high (>0.8) between seven of these SNPs (data not shown). The gene discussed is BCL2; the disease is endometrial cancer.