SHANK3 and schizophrenia: Gauthier et al. (2010) have used morpholinos to knock-down SHANK3, a gene linked to schizophrenia and ASD in human patients. shank3 morphant zebrafish show decreased swimming after being touched, a phenotype which can be rescued with a wild-type (but not a mutant) version of the corresponding rat gene. Therefore, this study validated alterations to shank3 as being important in the control of behavior, with potential implications for both schizophrenia and ASD.