SAMD4A and myotonic dystrophy type 1: In spite of the observation that SMAUG1-expressing DM1 myoblasts show reduced nuclear CUGBP1, we did not detect an increase on cytoplasmic CUGBP1 in DM1 myoblasts transfected with SMAUG1 when compared to GFP-transfected controls (Figure S3, see also western blot of cytoplasmic fraction in Figure 6A).