TLR9 and breast cancer: As TLR pathways are central in tissue repair and regeneration [19,54,55], we investigated several TLRs including TLR9. No GWAS studies to date have found that breast cancer risk is influenced by variants in TLR9. We found that rs352140 in TLR9 was associated with breast cancer risk (OR 0.85, 95% CI 0.74–0.97).