CACNA1B and larynx cancer: Among the drugs used for cancer of the larynx [26] (including cisplatin, 5-fluorouracil, carboplatin, and gemcitabine), both paclitaxel and docetaxel work by binding tubulin, notably with strong binding to βIIa and βIIb tubulin, then with less strength to βIII and βIV tubulin [30].