FMR1 and Global developmental delay: In this report, we describe a female patient with global developmental delays and a ~10.6 Mb deletion at Xq27.3-q28 (144,270,614-154,845,961 bp), a region that contains more than 100 genes including IDS and FMR1. X-inactivation studies and IDS activity assays were performed to determine the cause of her condition.