In this regard, it has been reported that CD56+ NK cells are more efficient in suppressing the growth of a lung cancer xenograft in SCID mice, if they are coinjected with either CD8+ T cells or unfractionated peripheral blood lymphocytes which are presumed to be important for the in situ secretion of NK cell stimulating cytokines [39,40]. This evidence concerns the gene CD8A and lung carcinoma.