IFNG and tuberculosis: The present study suggests that IFNG +874T/A, IFNG +2109A/G, IL12 +1188A/C, IL10 −819C/T, and TGFB1 +21C/T are associated with different cytokine levels in PTB patients and may play a role in the initiation and maintenance of acquired cellular immunity to TB and in the outcome of the active disease and antituberculosis treatment.