Third frontier holds DDR2, PPP1R1A, ARF4, and KPNA6. Changes in expression of DDR2 have been linked to several human cancers, for example, in non-small cell lung carcinoma (NSCLC) 28 and in nasopharyngeal carcinoma 29. The gene discussed is PPP1R1A; the disease is nasopharyngeal carcinoma.