GNA11 and uveal melanoma: Interestingly, our findings and those of Madic et al. 30 confirm and extend the observation by Raamsdonk et al. (2010) 18 that GNA11 codon Q209 mutations were more frequent than GNAQ codon Q209 mutations in metastatic uveal melanoma than in primary uveal melanoma – of the 12 mutations that we identified in either cfDNA or DNA from metastatic tissue, eight (66%) affected codon Q209 of GNA11. The ratios observed by the groups of Madic and Raamsdonk are almost identical with 14/21 (67%) and 13/18 (72%), respectively.