SNAI2 and neoplasm: On the other hand, VNR treatment weakly inhibited the tumor growth in A549/EGFP tumors, compared with in the vehicle control (19% of tumor reduction), while VNR treatment markedly inhibited tumor growth in A549/Slug tumors (64% of tumor reduction), clearly indicating that Slug overexpression markedly increased the drug sensitivity to VNR in vivo, similar to the results observed in vitro.