Thus, as evident from this study, the usefulness of serial determinations of serum CRP for the diagnosis and follow-up of bacterial infections can be relied upon, although its usefulness in the evaluation of neutropenic febrile patients with cancer has always been debated upon by many researchers, for it has been postulated that serum CRP levels can also be elevated as a consequence of the malignant process itself, irrespective of the presence of systemic bacterial infections [30]. This evidence concerns the gene CRP and cancer.