It has been reported that IECs, macrophages, and T cells secrete large amounts of chemokines such as IL-8 and pro-inflammatory cytokines including TNF-α, IL-6, IL-12, IL-17, IL-23, and interferon (IFN)-γ in the inflamed intestines of IBD patients [5]. This evidence concerns the gene CXCL8 and inflammatory bowel disease.