These results indicate that GRIM-19 and NDUFS3 expression levels are negatively, whereas HIF-1α, FN, integrin α5 and β1, and N-cadherin are positively, correlated with the invasive property in these breast cancer cell lines, which is in agreement with the observations in the G19 and p30 cells. This evidence concerns the gene NDUFS3 and breast cancer.