To elucidate the interaction between genotype and life stress on contextual fear conditioning and shed light on the absent conditioning effect regarding anxiety ratings in T+ allele carriers, correlations with the number of stressful life events were calculated, as stressful events were found to modulate the effects of 5HTTLPR and NPSR1 polymorphisms on levels of anxiety (Klauke et al., 2011, 2012; Klucken et al., 2013). Here, NPSR1 is linked to Anxiety.